What Is Idiopathic Immune-Mediated Thrombocytopenia in Dogs? The question is simple, but while answering you need to consider various factors.
Immune Medicated Thrombocytopenia is a condition where the immune system of the body starts to damage and destroy platelets. We know it well that the immune system is designed to fight healthy tissues, not germs.
In case of ITP, the immune system attacks platelets; the cells are mainly responsible for clotting the blood. If platelets are destroyed more, then spontaneous bleeding can occur. When a massive quantity of blood is lost, it may cause anemia.
The ITP is caused by an autoimmune attack against the platelets of dog, and usually, the initial cause of this is unknown. It can be primary issues or the secondary issues, triggered by other diseases.
If a dog with abnormal bleeding, your vet will need to do some tests to find the cause. The blood taste will show a low platelet count. However, you must know that the ITP is not the only cause of thrombocytopenia.
Signs of Idiopathic Immune-Mediated Thrombocytopenia
Blood of urine
Blood in vomit
Bruising on the skin
Bleeding from the nose or mouth
Blood in stool or black stool
How to Diagnosis
The diagnose is the process of elimination and determine the cause of the symptoms.
To determine the number of blood platelets, complete blood count is essential. Apart from this test other tests are also used for blood smear, serum chemistry profiled, and heartworm antigen testing and coagulation profile.
Blood samples can be collected with traumatic venipuncture to stop the activation of clotting factors. The confirmation depends on CBC test as well as blood smear test. It happens, if the immune-medicated thrombocytopenia has developed on rapid platelet depletion point.
The evaluation of the history of your dog will help you to determine if there is an instant change in your dogs like new medications or vaccinations. Try to give your vet as much information as possible like a daily routine, recent travelling and other changes in the activity.
The bone marrow is essential if concurrent leucopenia, with or without anemia. If it is performed, it can show an underlying cause which is not apparent through the clinical test.
Although the Idiopathic Immune Medicated is a complex and variable condition, so treatment is individualized. However, complete care is needed when the disorder is initially diagnosed, and many dogs need to be hospitalized instantly.
A number of dogs having Immune Medicated Thrombocytopenia will show fast improvement with prednisolone combination or alone under a week. After the stabilization with treatment, the doses are tapered down while monitoring the platelet value closely.
Despite appropriate treatment, around 10 to 15% of dogs with ITP can die or are euthanized at the starting of the disease or after the recurrence of their signs. For the positive output, follow all treatments set by your vet for your pooch. Provide all medication prescribed as directed by your veterinarian.